Mutation + Selection = Stasis

Mutation Selection StasisThe genetic mutation plus natural selection equation emerged as the most popular theory of biological evolution during the twentieth century. With advances in biotechnology, however, the credibility of this theory – popularly known as neo-Darwinism or the Modern Synthesis theory – has since been increasingly challenged by evolutionary scientists.

In an experimental evolution model using the yeast microbe Saccharomyces cerevisiae species, a recent study published in the journal Science by a Harvard research group undermines the theory of genetic mutations plus natural selection equals evolution. The model demonstrates stasis – not evolution.

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Gene Duplication-Driven Evolution

gene duplication
Charles Darwin‘s first reference to a “gene” appears in the 4th edition of The Origin of Species in 1866.  Since then, the gene has emerged as the essential molecular mechanism driving Darwin’s theory.

This intersection of natural selection with Gregor Mendel‘s theory of genetic inheritance was later named Modern Evolutionary Synthesis or The Modern Synthesis, largely based on Julian Huxley‘s 1942 book entitled Evolution. The Modern Synthesis.

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Ancient DNA Stability

Jurassic ParkPristine preservation of DNA is of critical importance in the study of ancient DNA. The structural integrity of the DNA molecule, contrary to the Jurassic Park tale, is not infinitely stable.

Damage to the DNA molecule in living organisms occurs naturally from normal metabolic and hydrolytic processes and from environmental factors such as ultraviolet light and radiation.

Damage to DNA in mammalian cells is known to occur 1 million times daily.  While alive organisms can identify and correct these damages, the evolution industry has been reticent to address the stability of ancient DNA in the fossil record.

 

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Coelacanth Genome

CoelacanthThe long-awaited analysis for one of the most influential lobed-finned fish in evolution history, the coelacanth genome (pictured left), was published last week by lead scientists Chris T. Amemiya (pictured right below) of the University of Washington and Jessica Alföldi from MIT and Harvard in the prestigious journal Nature.

The coelacanth plays a crucial and colorful role in the history of evolution. Biologist Louis Agassiz, born in Switzerland, became a professor at Harvard University and founder of the Museum of Comparative Biology, and was the first to describe and name the fish in 1839. Ironically, Agazzi became a leading critic of Charles Darwin.

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