First Synthetic Species

Mycoplasma mycoidesCraig Venter, the maverick American biologist and businessman captured worldwide attention by announcing the creation of “the first synthetic species,” nicknamed “Synthia.” Venter has the credentials. In 2000, Venter, along with Francis Collins of the National Institutes of Health, jointly announced the complete mapping of the human genome.

In a 60-Minute CBS interview with Steve Kroft (pictured right), in the aired TV segment entitled “J. Craig Venter: Designing Life,” CBS touted that Venter’s new synthetic species “gets its genetic instructions from a synthetic chromosome made by man, not nature.”

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Fate of Darwin’s Finches

GalapagosThe fate of Charles Darwin’s finches is a fascinating saga. Far from England on the equator in the Pacific Ocean lying more than 800 miles off the west coast of Ecuador, the finches Darwin captured on the Galapagos Islands (pictured left), except for one tag, are now missing. As one of the most controversial birds in modern history, the fate of Darwin’s finches belies their current iconic status.

Reaching the Galápagos Islands on September 15, 1835, more than four years after leaving England, the HMS Beagle started preparations to set sail from the island just five weeks later. Darwin had collected many different types of specimens during that time, some weighing up to 500 pounds each. Although typically an avid collector and note-taker, Darwin surprisingly did not record the number of finches collected nor the number loaded onto the ship.

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Longest Evolution Experiment Dead-End

The industry’s longest-running research experiment reached a milestone in October, studying the evolution of more than 68,000 generations.

Biologist Richard Lenski started the now legendary experiment in his laboratory early in 1988 with just 12 flasks seeded with genetically identical bacteria known as Escherichia coli (E. coli).

Since then, the bacteria have been growing in a carefully measured solution of glucose, a type of sugar—”food” for bacteria. Each flask contained just a sparse amount of glucose to create a stressful environment, along with a high concentration of citrate, a molecular close cousin of glucose, pushing the bacteria to evolve. Since 1988, Lenski’s laboratory team has transferred a small sample of the new 50 mL Erlenmeyer flasks every day.

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Galapagos Icon of Evolution

In 1835, the Galapagos Islands piqued a young British naturalist’s endless curiosity. Equipped with technologies not much beyond a clock, compass, measuring tape, scale, thermometer, clinometer, and microscope, the experience eventually propelled Charles Darwin to propose a new world-shattering theory of evolution in his 1859 book–The Origin of Species.

Since then, technological advances have revolutionized scientific investigations upending Darwin’s finches with a new Galapagos icon of evolution.

 

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New Evolution Nightmare

Syn3.0J. Craig Venter, best known for being the first to sequence the human genome in 2000, is recognized as one of the leading scientists of the 21st century. Ten years after his important accomplishment, Venter was credited for successfully recreating “the first synthetic species” in 2010 – named Mycoplasma laboratorium.

In his relentless pursuit to “understand the molecular and biological function of every gene in a cell,” Venter released the latest findings discovered in his genetics research laboratory in Southern California. The paper, entitled “Design and Synthesis of a Minimal Bacterial Genome,” was published on March 25, 2016, in the journal Science. The findings have emerged as a new genomic evolution nightmare for Craig Venter.

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